Detecting myocardial ischemia with 2

Detecting myocardial ischemia with 2-D CVIB imaging method--an in vivo animal experiment study

A 2-D cyclic variation of integrated backscatter (CVIB) imaging method was established for detecting myocardial ischemia. To demonstrate the feasibility and validity of this method, animal experiments were conducted. Acute myocardial ischemia was induced by occluding left anterior descending coronary artery in 10 anesthetized open-chest dogs. While scanning the normal hearts and the ischemic hearts with a B scanner, digital radiofrequency data were acquired by a real-time acquisition system in synchronism. The offline analysis to the radio-frequency signal with the 2-D CVIB imaging method was performed to verify the consistency between the imaging result and the design of the experiment. In addition, 4 dogs in experiment were treated with the heart pacemaker in order to investigate the influence of changing in heart rate on the detection of ischemic myocardium with the proposed method. The experimental result showed that the 2-D CVIB imaging method succeeded in detecting the ischemic myocardium and is a new non-invasive way for the cardiologists to both quantitatively and visually evaluate the contractile performance of the myocardium.

作 者： JIANG Yong BAI Jing YING Kui CHENG Kezheng YU Can   作者单位： JIANG Yong,BAI Jing,YING Kui,YU Can(Department of Biomedical Engineering, Tsinghua Univeristy, Beijing 100084, China)

CHENG Kezheng(Fuwai Hospital, Beijing 100037, China) 

刊 名： 自然科学进展(英文版)  SCI 英文刊名： PROGRESS IN NATURAL SCIENCE  年，卷(期)： 2004 14(11)  分类号： Q95  关键词： integrated backscatter (IB)   myocardial ischemia   cyclic variation of integrated backscatter (CVIB)   animal study  

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